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Effects of adrenergic-stimulated lipolysis and cytokine production on in vitro mouse adipose tissue–islet interactions

Inflammatory cytokines and non-esterified fatty acids (NEFAs) are obesity-linked factors that disturb insulin secretion. The aim of this study was to investigate whether pancreatic adipose tissue (pWAT) is able to generate a NEFA/cytokine overload within the pancreatic environment and as consequence...

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Bibliographic Details
Main Authors: Oquendo, Morgana Barroso, Lorza-Gil, Estela, Juarez-Lopez, David, Wagner, Robert, Birkenfeld, Andreas L., Ullrich, Susanne, Gerst, Felicia
Format: Online Article Text
Language:English
Published: Nature Publishing Group UK 2022
Subjects:
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499973/
https://www.ncbi.nlm.nih.gov/pubmed/36138030
http://dx.doi.org/10.1038/s41598-022-18262-0