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Experimental reproducibility limits the correlation between mRNA and protein abundances in tumor proteomic profiles

Large-scale studies of human proteomes have revealed only a moderate correlation between mRNA and protein abundances. It is unclear to what extent this moderate correlation reflects post-transcriptional regulation and to what extent it reflects measurement error. Here, by analyzing replicate profile...

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Detalles Bibliográficos
Autores principales: Upadhya, Swathi Ramachandra, Ryan, Colm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499981/
https://www.ncbi.nlm.nih.gov/pubmed/36160043
http://dx.doi.org/10.1016/j.crmeth.2022.100288