Ca(v)2.2-NFAT2-USP43 axis promotes invadopodia formation and breast cancer metastasis through cortactin stabilization

Distant metastasis is the main cause of mortality in breast cancer patients. Using the breast cancer genomic data from The Cancer Genome Atlas (TCGA), we identified brain specific Ca(v)2.2 as a critical regulator of metastasis. Ca(v)2.2 expression is significantly upregulated in breast cancer and it...

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Detalles Bibliográficos
Autores principales: Xue, Ying, Li, Min, Hu, Jie, Song, Yuanlin, Guo, Wei, Miao, Changhong, Ge, Di, Hou, Yingyong, Wang, Xuefei, Huang, Xingxu, Liu, Tianshu, Zhang, Xiaoping, Huang, Qihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500045/
https://www.ncbi.nlm.nih.gov/pubmed/36137995
http://dx.doi.org/10.1038/s41419-022-05174-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500045/
https://www.ncbi.nlm.nih.gov/pubmed/36137995
http://dx.doi.org/10.1038/s41419-022-05174-0

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