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Peripheral interleukin-6-associated microglial QUIN elevation in basolateral amygdala contributed to cognitive dysfunction in a mouse model of postoperative delirium

BACKGROUND: Developing effective approaches for postoperative delirium has been hampered due to the lack of a pathophysiologically similar animal model to offer insights into the pathogenesis. The study, therefore, aimed to develop a delirium-like mouse model and explore the underlying mechanism. ME...

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Detalles Bibliográficos
Autores principales: Mu, Jing-Lan, Liu, Xiao-Dong, Dong, Ye-Hong, Fang, Ying-Ying, Qiu, Shi-Da, Zhang, Fu, Liu, Ke-Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500157/
https://www.ncbi.nlm.nih.gov/pubmed/36160165
http://dx.doi.org/10.3389/fmed.2022.998397