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WIPI proteins: Biological functions and related syndromes

WIPI (WD-repeat protein Interacting with PhosphoInositides) are important effectors in autophagy. These proteins bind phosphoinositides and recruit autophagy proteins. In mammals, there are four WIPI proteins: WIPI1, WIPI2, WIPI3 (WDR45B), and WIPI4 (WDR45). These proteins consist of a seven-bladed...

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Detalles Bibliográficos
Autores principales: Almannai, Mohammed, Marafi, Dana, El-Hattab, Ayman W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500159/
https://www.ncbi.nlm.nih.gov/pubmed/36157071
http://dx.doi.org/10.3389/fnmol.2022.1011918