Misfolding at the synapse: A role in amyotrophic lateral sclerosis pathogenesis?

A growing wave of evidence has placed the concept of protein homeostasis at the center of the pathogenesis of amyotrophic lateral sclerosis (ALS). This is due primarily to the presence of pathological transactive response DNA-binding protein (TDP-43), fused in sarcoma (FUS) or superoxide dismutase-1...

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Detalles Bibliográficos
Autores principales: Lum, Jeremy S., Yerbury, Justin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500160/
https://www.ncbi.nlm.nih.gov/pubmed/36157072
http://dx.doi.org/10.3389/fnmol.2022.997661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500160/
https://www.ncbi.nlm.nih.gov/pubmed/36157072
http://dx.doi.org/10.3389/fnmol.2022.997661

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