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Transcriptional regulation of INK4/ARF locus by cis and trans mechanisms
9p21 locus is one of the most reproducible regions in genome-wide association studies (GWAS). The region harbors CDKN2A/B genes that code for p16(INK4a), p15(INK4b), and p14(ARF) proteins, and it also harbors a long gene desert adjacent to these genes. The polymorphisms that are associated with seve...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500187/ https://www.ncbi.nlm.nih.gov/pubmed/36158211 http://dx.doi.org/10.3389/fcell.2022.948351 |