Glycolytic potential enhanced by blockade of pyruvate influx into mitochondria sensitizes prostate cancer to detection and radiotherapy

OBJECTIVE: This study aimed to evaluate the effects of mitochondrial pyruvate carrier (MPC) blockade on the sensitivity of detection and radiotherapy of prostate cancer (PCa). METHODS: We investigated glycolysis reprogramming and MPC changes in patients with PCa by using metabolic profiling, RNA-Seq...

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Detalles Bibliográficos
Autores principales: Xu, Huan, Chen, Junyi, Cao, Zhi, Chen, Xi, Huang, Caihong, Ji, Jin, Xu, Yalong, Jiang, Junfeng, Wang, Yue, Xu, Guowang, Zhou, Lina, He, Jingyi, Wei, Xuedong, Wu, Jason Boyang, Wang, Zhong, Ren, Shancheng, Wang, Fubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500223/
https://www.ncbi.nlm.nih.gov/pubmed/35972052
http://dx.doi.org/10.20892/j.issn.2095-3941.2021.0638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500223/
https://www.ncbi.nlm.nih.gov/pubmed/35972052
http://dx.doi.org/10.20892/j.issn.2095-3941.2021.0638

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