How Mycobacterium tuberculosis drug resistance has shaped anti-tubercular drug discovery

Drug resistance is an increasing problem for the treatment of tuberculosis. The prevalence of clinical isolates with pre-existing resistance needs to be considered in any drug discovery program. Non-specific mechanisms of resistance such as increased efflux or decreased permeability need to be consi...

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Detalles Bibliográficos
Autores principales: Bhagwat, Amala, Deshpande, Aditi, Parish, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500310/
https://www.ncbi.nlm.nih.gov/pubmed/36159638
http://dx.doi.org/10.3389/fcimb.2022.974101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500310/
https://www.ncbi.nlm.nih.gov/pubmed/36159638
http://dx.doi.org/10.3389/fcimb.2022.974101

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