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How Mycobacterium tuberculosis drug resistance has shaped anti-tubercular drug discovery
Drug resistance is an increasing problem for the treatment of tuberculosis. The prevalence of clinical isolates with pre-existing resistance needs to be considered in any drug discovery program. Non-specific mechanisms of resistance such as increased efflux or decreased permeability need to be consi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500310/ https://www.ncbi.nlm.nih.gov/pubmed/36159638 http://dx.doi.org/10.3389/fcimb.2022.974101 |