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No evidence for widespread positive selection on double substitutions within codons in primates and yeasts

Nucleotide substitutions in protein-coding genes can be divided into synonymous (S) and non-synonymous (N) ones that alter amino acids (including nonsense mutations causing stop codons). The S substitutions are expected to have little effect on function. The N substitutions almost always are affecte...

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Detalles Bibliográficos
Autores principales: Belinky, Frida, Bykova, Anastassia, Yurchenko, Vyacheslav, Rogozin, Igor B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500374/
https://www.ncbi.nlm.nih.gov/pubmed/36159983
http://dx.doi.org/10.3389/fgene.2022.991249