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No evidence for widespread positive selection on double substitutions within codons in primates and yeasts
Nucleotide substitutions in protein-coding genes can be divided into synonymous (S) and non-synonymous (N) ones that alter amino acids (including nonsense mutations causing stop codons). The S substitutions are expected to have little effect on function. The N substitutions almost always are affecte...
Autores principales: | Belinky, Frida, Bykova, Anastassia, Yurchenko, Vyacheslav, Rogozin, Igor B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500374/ https://www.ncbi.nlm.nih.gov/pubmed/36159983 http://dx.doi.org/10.3389/fgene.2022.991249 |
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