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Simvastatin and fluvastatin attenuate trauma-induced cell death and catabolism in human cartilage

Joint injuries are known to induce pathomechanisms that might lead to posttraumatic osteoarthritis (PTOA). In this regard, statins with their pleiotropic effects could represent potential therapeutic agents in preventing the development of PTOA. Therefore, we investigated the effects of simvastatin...

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Detalles Bibliográficos
Autores principales: Riegger, Jana, Maurer, Svenja, Pulasani, Sai, Brenner, Rolf E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500391/
https://www.ncbi.nlm.nih.gov/pubmed/36159664
http://dx.doi.org/10.3389/fbioe.2022.965302