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Simvastatin and fluvastatin attenuate trauma-induced cell death and catabolism in human cartilage
Joint injuries are known to induce pathomechanisms that might lead to posttraumatic osteoarthritis (PTOA). In this regard, statins with their pleiotropic effects could represent potential therapeutic agents in preventing the development of PTOA. Therefore, we investigated the effects of simvastatin...
Autores principales: | Riegger, Jana, Maurer, Svenja, Pulasani, Sai, Brenner, Rolf E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500391/ https://www.ncbi.nlm.nih.gov/pubmed/36159664 http://dx.doi.org/10.3389/fbioe.2022.965302 |
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