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Quantifying the transport of biologics across intestinal barrier models in real-time by fluorescent imaging

Unsuccessful clinical translation of orally delivered biological drugs remains a challenge in pharmaceutical development and has been linked to insufficient mechanistic understanding of intestinal drug transport. Live cell imaging could provide such mechanistic insights by directly tracking drug tra...

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Detalles Bibliográficos
Autores principales: Weller, Arjen, Hansen, Morten B., Marie, Rodolphe, Hundahl, Adam C., Hempel, Casper, Kempen, Paul J., Frandsen, Henrik L., Parhamifar, Ladan, Larsen, Jannik B., Andresen, Thomas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500407/
https://www.ncbi.nlm.nih.gov/pubmed/36159696
http://dx.doi.org/10.3389/fbioe.2022.965200