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CARD8 makes coxsackievirus more “heartbreaking”
In this issue of JEM, Nadkarni et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20212117) identify CARD8 as an innate sensor triggered by coxsackievirus B3 proteases to drive pyroptosis of aortic endothelial cells and cardiac myocytes, fueling viral replication and heart inflammation.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500452/ https://www.ncbi.nlm.nih.gov/pubmed/36129454 http://dx.doi.org/10.1084/jem.20221240 |