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Functional implication of ubiquitinating and deubiquitinating mechanisms in TDP-43 proteinopathies
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which motor neurons in spinal cord and motor cortex are progressively lost. About 15% cases of ALS also develop the frontotemporal dementia (FTD), in which the frontotemporal lobar degeneration (FTLD) occurs in the frontal a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500471/ https://www.ncbi.nlm.nih.gov/pubmed/36158183 http://dx.doi.org/10.3389/fcell.2022.931968 |