In vitro characterization and rational analog design of a novel inhibitor of telomerase assembly in MDA MB 231 breast cancer cell line

Tumor cells have unlimited replicative potential, principally due to telomerase activity, which requires assembly of components such as dyskerin (hDKC1), human telomerase reverse transcriptase and human telomerase RNA (hTR). The present study aimed to develop novel inhibitors of telomerase to target...

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Detalles Bibliográficos
Autores principales: Armando, Romina, Cabrera, Maia, Vilarullo, Roman, Chinestrad, Patricio, Maggio, Julian, Paderta, Camila, Menna, Pablo Lorenzano, Gomez, Daniel, Mengual Gómez, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500588/
https://www.ncbi.nlm.nih.gov/pubmed/36102322
http://dx.doi.org/10.3892/or.2022.8403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500588/
https://www.ncbi.nlm.nih.gov/pubmed/36102322
http://dx.doi.org/10.3892/or.2022.8403

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