Identification of Novel Loci Involved in Adalimumab Response in Crohn’s Disease Patients Using Integration of Genome Profiling and Isoform-Level Immune-Cell Deconvoluted Transcriptome Profiling of Colon Tissue

Crohn’s disease is a consequence of dysregulated inflammatory response to the host’s microbiota. Although anti-TNF treatment improves the quality of the patient’s life, a large proportion of patients lose response to the treatment. The past decade of research has led to a continuum of studies showca...

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Detalles Bibliográficos
Autores principales: Gorenjak, Mario, Jezernik, Gregor, Krušič, Martina, Skok, Pavel, Potočnik, Uroš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500628/
https://www.ncbi.nlm.nih.gov/pubmed/36145641
http://dx.doi.org/10.3390/pharmaceutics14091893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500628/
https://www.ncbi.nlm.nih.gov/pubmed/36145641
http://dx.doi.org/10.3390/pharmaceutics14091893

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