Myofibrillar Lattice Remodeling Is a Structural Cytoskeletal Predictor of Diaphragm Muscle Weakness in a Fibrotic mdx (mdx Cmah(−/−)) Model

Duchenne muscular dystrophy (DMD) is a degenerative genetic myopathy characterized by complete absence of dystrophin. Although the mdx mouse lacks dystrophin, its phenotype is milder compared to DMD patients. The incorporation of a null mutation in the Cmah gene led to a more DMD-like phenotype (i.e...

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Detalles Bibliográficos
Autores principales: Ritter, Paul, Nübler, Stefanie, Buttgereit, Andreas, Smith, Lucas R., Mühlberg, Alexander, Bauer, Julian, Michael, Mena, Kreiß, Lucas, Haug, Michael, Barton, Elisabeth, Friedrich, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500669/
https://www.ncbi.nlm.nih.gov/pubmed/36142754
http://dx.doi.org/10.3390/ijms231810841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500669/
https://www.ncbi.nlm.nih.gov/pubmed/36142754
http://dx.doi.org/10.3390/ijms231810841

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