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Nanostructured Lipid Carrier-Based Codelivery of Raloxifene and Naringin: Formulation, Optimization, In Vitro, Ex Vivo, In Vivo Assessment, and Acute Toxicity Studies

This work aimed to develop dual drug-loaded nanostructured lipid carriers of raloxifene and naringin (RLX/NRG NLCs) for breast cancer. RLX/NRG NLCs were prepared using Compritol 888 ATO and oleic acid using a hot homogenization–sonication method and optimized using central composite design (CCD). Th...

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Detalles Bibliográficos
Autores principales: Alhalmi, Abdulsalam, Amin, Saima, Khan, Zafar, Beg, Sarwar, Al kamaly, Omkulthom, Saleh, Asmaa, Kohli, Kanchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500671/
https://www.ncbi.nlm.nih.gov/pubmed/36145519
http://dx.doi.org/10.3390/pharmaceutics14091771