Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model

As energy metabolism regulation factor, peroxisome proliferator-activated receptor (PPAR) is thought to be a potential target for the treatment of depression. The present study was performed to evaluate the effects of activating PPARβ/δ, the most highly expressed subtype in the brain, in depressive...

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Detalles Bibliográficos
Autores principales: Ji, Juan, Li, Shangze, Jiang, Zikai, Yu, Jianbing, Sun, Yuqin, Cai, Zhenyu, Dong, Yinfeng, Sun, Xiulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500741/
https://www.ncbi.nlm.nih.gov/pubmed/36142731
http://dx.doi.org/10.3390/ijms231810822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500741/
https://www.ncbi.nlm.nih.gov/pubmed/36142731
http://dx.doi.org/10.3390/ijms231810822

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