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Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model
As energy metabolism regulation factor, peroxisome proliferator-activated receptor (PPAR) is thought to be a potential target for the treatment of depression. The present study was performed to evaluate the effects of activating PPARβ/δ, the most highly expressed subtype in the brain, in depressive...
Autores principales: | Ji, Juan, Li, Shangze, Jiang, Zikai, Yu, Jianbing, Sun, Yuqin, Cai, Zhenyu, Dong, Yinfeng, Sun, Xiulan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500741/ https://www.ncbi.nlm.nih.gov/pubmed/36142731 http://dx.doi.org/10.3390/ijms231810822 |
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