Comparative Study of Chemical Stability of a PK20 Opioid–Neurotensin Hybrid Peptide and Its Analogue [Ile(9)]PK20—The Effect of Isomerism of a Single Amino Acid

Chemical stability is one of the main problems during the discovery and development of potent drugs. When ignored, it may lead to unreliable biological and pharmacokinetics data, especially regarding the degradation of products’ possible toxicity. Recently, two biologically active drug candidates we...

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Detalles Bibliográficos
Autores principales: Żyżyńska-Granica, Barbara, Mollica, Adriano, Stefanucci, Azzurra, Granica, Sebastian, Kleczkowska, Patrycja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500858/
https://www.ncbi.nlm.nih.gov/pubmed/36142749
http://dx.doi.org/10.3390/ijms231810839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500858/
https://www.ncbi.nlm.nih.gov/pubmed/36142749
http://dx.doi.org/10.3390/ijms231810839

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