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Comparative Study of Chemical Stability of a PK20 Opioid–Neurotensin Hybrid Peptide and Its Analogue [Ile(9)]PK20—The Effect of Isomerism of a Single Amino Acid
Chemical stability is one of the main problems during the discovery and development of potent drugs. When ignored, it may lead to unreliable biological and pharmacokinetics data, especially regarding the degradation of products’ possible toxicity. Recently, two biologically active drug candidates we...
Autores principales: | Żyżyńska-Granica, Barbara, Mollica, Adriano, Stefanucci, Azzurra, Granica, Sebastian, Kleczkowska, Patrycja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500858/ https://www.ncbi.nlm.nih.gov/pubmed/36142749 http://dx.doi.org/10.3390/ijms231810839 |
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