Structural Insights into the Phosphorylation-Enhanced Deubiquitinating Activity of UCHL3 and Ubiquitin Chain Cleavage Preference Analysis

Ubiquitin C-terminal hydrolase-L3 (UCHL3), an important member of the ubiquitin C-terminal hydrolase family, is involved in DNA repair and cancer development. UCHL3 can cleave only complexes of monoubiquitin and its conjugates, such as Ub-AMC, His, or small ubiquitin-like modifier, but not polyubiqu...

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Detalles Bibliográficos
Autores principales: Ren, Yujing, Yu, Beiming, Zhou, Lihui, Wang, Feng, Wang, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501053/
https://www.ncbi.nlm.nih.gov/pubmed/36142702
http://dx.doi.org/10.3390/ijms231810789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501053/
https://www.ncbi.nlm.nih.gov/pubmed/36142702
http://dx.doi.org/10.3390/ijms231810789

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