Design of Smart Nanodiamonds: Introducing pH Sensitivity to Improve Nucleic Acid Carrier Efficiency of Diamoplexes

The mechanism of cellular uptake and intracellular fate of nanodiamond/nucleic acid complexes (diamoplexes) are major determinants of its performance as a gene carrier. Our group designed lysine-nanodiamonds (K-NDs) as vectors for nucleic acid delivery. In this work, we modified the surface of K-NDs...

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Detalles Bibliográficos
Autores principales: Alwani, Saniya, Rai, Raj, Zittlau, Isabella, Rekve, Jonathan, Michel, Deborah, Badea, Ildiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501119/
https://www.ncbi.nlm.nih.gov/pubmed/36145542
http://dx.doi.org/10.3390/pharmaceutics14091794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501119/
https://www.ncbi.nlm.nih.gov/pubmed/36145542
http://dx.doi.org/10.3390/pharmaceutics14091794

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