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A Pharmacokinetic Dose-Optimization Study of Cabotegravir and Bictegravir in a Mouse Pregnancy Model

Animal pregnancy models can be useful tools to study HIV antiretroviral safety and toxicity and to perform mechanistic studies that are not easily performed in humans. Utilization of clinically relevant dosing in these models improves the relevance of the findings. Cabotegravir and bictegravir are n...

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Detalles Bibliográficos
Autores principales: Mohan, Haneesha, Atkinson, Kieran, Watson, Birgit, Brumme, Chanson J., Serghides, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501129/
https://www.ncbi.nlm.nih.gov/pubmed/36145509
http://dx.doi.org/10.3390/pharmaceutics14091761