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Investigation of Anxiety- and Depressive-like Symptoms in 4- and 8-Month-Old Male Triple Transgenic Mouse Models of Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common form of dementia. Approximately 50% of AD patients show anxiety and depressive symptoms, which may contribute to cognitive decline. We aimed to investigate whether the triple-transgenic mouse (3xTg-AD) is a good...

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Detalles Bibliográficos
Autores principales: Várkonyi, Dorottya, Török, Bibiána, Sipos, Eszter, Fazekas, Csilla Lea, Bánrévi, Krisztina, Correia, Pedro, Chaves, Tiago, Farkas, Szidónia, Szabó, Adrienn, Martínez-Bellver, Sergio, Hangya, Balázs, Zelena, Dóra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501136/
https://www.ncbi.nlm.nih.gov/pubmed/36142737
http://dx.doi.org/10.3390/ijms231810816