Biophysical Characterization of LTX-315 Anticancer Peptide Interactions with Model Membrane Platforms: Effect of Membrane Surface Charge

LTX-315 is a clinical-stage, anticancer peptide therapeutic that disrupts cancer cell membranes. Existing mechanistic knowledge about LTX-315 has been obtained from cell-based biological assays, and there is an outstanding need to directly characterize the corresponding membrane-peptide interactions...

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Detalles Bibliográficos
Autores principales: Koo, Dong Jun, Sut, Tun Naw, Tan, Sue Woon, Yoon, Bo Kyeong, Jackman, Joshua A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501188/
https://www.ncbi.nlm.nih.gov/pubmed/36142470
http://dx.doi.org/10.3390/ijms231810558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501188/
https://www.ncbi.nlm.nih.gov/pubmed/36142470
http://dx.doi.org/10.3390/ijms231810558

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