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In Silico Pharmacokinetic Profiling of the Identified Bioactive Metabolites of Pergularia tomentosa L. Latex Extract and In Vitro Cytotoxic Activity via the Induction of Caspase-Dependent Apoptosis with S-Phase Arrest

The in vitro cytotoxic efficacy of plant latex from Pergularia tomentosa L. was studied using five human cancer cell lines: HeLa cells (cervical carcinoma cells), A-549 (lung carcinoma), Panc-1 (pancreatic carcinoma cells), MDA-MB-231 (metastatic mammary adenocarcinoma), and MRC-5 (lung fibroblast c...

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Detalles Bibliográficos
Autores principales: Abouzied, Amr S., Abd-Rabo, Marwa M., Huwaimel, Bader, Almahmoud, Suliman A., Almarshdi, Afnan Abdulkareem, Alharbi, Fai Mutaz, Alenzi, Sulafa Salem, Albsher, Bayan Naef, Alafnan, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501251/
https://www.ncbi.nlm.nih.gov/pubmed/36145353
http://dx.doi.org/10.3390/ph15091132