Brain Targeting of Quetiapine Fumarate via Intranasal Delivery of Loaded Lipospheres: Fabrication, In-Vitro Evaluation, Optimization, and In-Vivo Assessment

A liposphere system for intranasal delivery of quetiapine fumarate (QTF) was created to assess the potential for enhanced drug delivery. We investigated the effects of particle size, entrapment effectiveness, poly dispersibility index, and pluronic incorporation percentage on these variables. The op...

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Detalles Bibliográficos
Autores principales: Zaki, Randa Mohammed, Aldawsari, Mohammed F., Alossaimi, Manal A., Alzaid, Shaikah F., Devanathadesikan Seshadri, Vidya, Almurshedi, Alanood S., Aldosari, Basmah Nasser, Yusif, Rehab Mohammad, Sayed, Ossama M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501298/
https://www.ncbi.nlm.nih.gov/pubmed/36145303
http://dx.doi.org/10.3390/ph15091083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501298/
https://www.ncbi.nlm.nih.gov/pubmed/36145303
http://dx.doi.org/10.3390/ph15091083

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