New Sulfamethoxazole Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors: Design, Synthesis, Cytotoxic Activity and Molecular Modeling

In this study new sulphamethoxazole derivatives (S1–S4, S6–S12, and S14–S22) were designed and synthesized and their structures were fully characterized and validated using NMR, mass, and IR spectroscopy, as well as elemental analyses. All new derivatives (S1–S22) were assayed against human carbonic...

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Detalles Bibliográficos
Autores principales: Abdelgawad, Mohamed A., Bukhari, Syed N. A., Musa, Arafa, Elmowafy, Mohammed, Elkomy, Mohammed H., Nayl, AbdElAziz. A., El-Ghorab, Ahmed H., Alsohaimi, Ibrahim Hotan, Abdel-Bakky, Mohamed Sadek, Althobaiti, Ibrahim O., Altaleb, Hamud A., Omar, Hany A., Abdelazeem, Ahmed H., Zaki, Mohamed A., Shaker, Mohamed E., Elshemy, Heba A. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501356/
https://www.ncbi.nlm.nih.gov/pubmed/36145355
http://dx.doi.org/10.3390/ph15091134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501356/
https://www.ncbi.nlm.nih.gov/pubmed/36145355
http://dx.doi.org/10.3390/ph15091134

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