New Diarylamine K(V)10.1 Inhibitors and Their Anticancer Potential

Expression of the voltage-gated potassium channel K(V)10.1 (Eag1) has been detected in over 70% of human cancers, making the channel a promising new target for new anticancer drug discovery. A new structural class of K(V)10.1 inhibitors was prepared by structural optimisation and exploration of the...

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Detalles Bibliográficos
Autores principales: Gubič, Špela, Toplak, Žan, Shi, Xiaoyi, Dernovšek, Jaka, Hendrickx, Louise Antonia, Pinheiro-Junior, Ernesto Lopes, Peigneur, Steve, Tytgat, Jan, Pardo, Luis A., Peterlin Mašič, Lucija, Tomašič, Tihomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501377/
https://www.ncbi.nlm.nih.gov/pubmed/36145712
http://dx.doi.org/10.3390/pharmaceutics14091963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501377/
https://www.ncbi.nlm.nih.gov/pubmed/36145712
http://dx.doi.org/10.3390/pharmaceutics14091963

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