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LBMPL Vaccine Therapy Induces Progressive Organization of the Spleen Microarchitecture, Improved Th1 Adaptative Immune Response and Control of Parasitism in Leishmania infantum Naturally Infected Dogs

The spleen plays a central role in human and canine visceral leishmaniasis, where the activation of the immune response occurs in one of the tissues where Leishmania infantum reproduces. Therefore, this organ is both a target to understand the mechanisms involved in the parasite control and a parame...

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Detalles Bibliográficos
Autores principales: Roatt, Bruno Mendes, de Oliveira Cardoso, Jamille Mirelle, Reis, Levi Eduardo Soares, Moreira, Gabriel José Lucas, Gonçalves, Letícia Captein, de Souza Marques, Flávia, das Dores Moreira, Nádia, de Abreu Vieira, Paula Melo, de Oliveira Aguiar-Soares, Rodrigo Dian, Giunchetti, Rodolfo Cordeiro, Reis, Alexandre Barbosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501398/
https://www.ncbi.nlm.nih.gov/pubmed/36145406
http://dx.doi.org/10.3390/pathogens11090974