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MF59 Promoted the Combination of CpG ODN1826 and MUC1-MBP Vaccine-Induced Antitumor Activity Involved in the Enhancement of DC Maturation by Prolonging the Local Retention Time of Antigen and Down-Regulating of IL-6/STAT3

Our previous study found that CpG oligodeoxynucleotides 1826 (CpG 1826), combined with mucin 1 (MUC1)-maltose-binding protein (MBP) (M-M), had certain antitumor activity. However, this combination is less than ideal for tumor suppression (tumors vary in size and vary widely among individuals), with...

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Detalles Bibliográficos
Autores principales: Jie, Jing, Liu, Guomu, Feng, Jingyue, Huo, Desheng, Wu, Yixuan, Yuan, Hongyan, Tai, Guixiang, Ni, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501507/
https://www.ncbi.nlm.nih.gov/pubmed/36142800
http://dx.doi.org/10.3390/ijms231810887