Cargando…

Fragment-Based and Structural Investigation for Discovery of JNK3 Inhibitors

The c-Jun N-terminal kinases (JNKs) are members of the mitogen-activated protein kinase (MAPK) family and are related to cell proliferation, gene expression, and cell death. JNK isoform 3 (JNK3) is an important therapeutic target in varieties of pathological conditions including cancers and neuronal...

Descripción completa

Detalles Bibliográficos
Autores principales: Duong, Men Thi Hoai, Ahn, Hee-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501523/
https://www.ncbi.nlm.nih.gov/pubmed/36145648
http://dx.doi.org/10.3390/pharmaceutics14091900