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Conjugation of a Cationic Cell-Penetrating Peptide with a Novel Kunitzin-like Trypsin Inhibitor: New Insights for Enhancement of Peptide Bioactivities
Cationic cell-penetrating peptides (CPPs), such as transactivator of transcription (TAT) peptide, have been proposed as effective drug carriers to improve intracellular delivery of biological macromolecules. Amphibian skin-derived Kunitz-type trypsin inhibitors (KTIs), short counterparts of KTIs fro...
Autores principales: | Yao, Junting, Yin, Weining, Chen, Yuqing, Chen, Xiaoling, Jiang, Yangyang, Wang, Tao, Ma, Chengbang, Zhou, Mei, Chen, Tianbao, Shaw, Chris, Wang, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501525/ https://www.ncbi.nlm.nih.gov/pubmed/36145553 http://dx.doi.org/10.3390/pharmaceutics14091805 |
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