Identification of Gedunin from a Phytochemical Depository as a Novel Multidrug Resistance-Bypassing Tubulin Inhibitor of Cancer Cells

The chemotherapy of tumors is frequently limited by the development of resistance and severe side effects. Phytochemicals may offer promising candidates to meet the urgent requirement for new anticancer drugs. We screened 69 phytochemicals, and focused on gedunin to analyze its molecular modes of ac...

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Detalles Bibliográficos
Autores principales: Khalid, Sami A., Dawood, Mona, Boulos, Joelle C., Wasfi, Monica, Drif, Assia, Bahramimehr, Faranak, Shahhamzehei, Nasim, Shan, Letian, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501561/
https://www.ncbi.nlm.nih.gov/pubmed/36144591
http://dx.doi.org/10.3390/molecules27185858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501561/
https://www.ncbi.nlm.nih.gov/pubmed/36144591
http://dx.doi.org/10.3390/molecules27185858

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