AST-487 Inhibits RET Kinase Driven TERT Expression in Bladder Cancer

Mutations in the promoter of the human Telomerase Reverse Transcriptase (hTERT) gene are common and associated with its elevated expression in bladder cancer, melanoma, and glioblastoma. Though these mutations and TERT overexpression are associated with aggressive disease and poor outcome, an incomp...

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Detalles Bibliográficos
Autores principales: Agarwal, Neeraj, Zhou, Qiong, Arya, Deepak, Rinaldetti, Sébastien, Duex, Jason, LaBarbera, Daniel V., Theodorescu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501578/
https://www.ncbi.nlm.nih.gov/pubmed/36142729
http://dx.doi.org/10.3390/ijms231810819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501578/
https://www.ncbi.nlm.nih.gov/pubmed/36142729
http://dx.doi.org/10.3390/ijms231810819

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