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Characterization of Hyaluronidase 4 Involved in the Catabolism of Chondroitin Sulfate

Hyaluronidases (HYALs) are endo-beta-N-acetylhexosaminidases that depolymerize not only hyaluronan but also chondroitin sulfate (CS) at the initial step of their catabolism. Although HYAL1 hydrolyzes both CS and HA, HYAL4 is a CS-specific endoglycosidase. The substrate specificity of HYAL4 and ident...

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Detalles Bibliográficos
Autores principales: Yamada, Shuhei, Mizumoto, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501593/
https://www.ncbi.nlm.nih.gov/pubmed/36144836
http://dx.doi.org/10.3390/molecules27186103