SNAI1-dependent upregulation of CD73 increases extracellular adenosine release to mediate immune suppression in TNBC

Triple-negative subtype of breast cancer (TNBC) is hallmarked by frequent disease relapse and shows highest mortality rate. Although PD-1/PD-L1 immune checkpoint blockades have recently shown promising clinical benefits, the overall response rate remains largely insufficient. Hence, alternative ther...

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Detalles Bibliográficos
Autores principales: Hasmim, Meriem, Xiao, Malina, Van Moer, Kris, Kumar, Akinchan, Oniga, Alexandra, Mittelbronn, Michel, Duhem, Caroline, Chammout, Anwar, Berchem, Guy, Thiery, Jean Paul, Volpert, Marianna, Hollier, Brett, Noman, Muhammad Zaeem, Janji, Bassam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501677/
https://www.ncbi.nlm.nih.gov/pubmed/36159844
http://dx.doi.org/10.3389/fimmu.2022.982821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501677/
https://www.ncbi.nlm.nih.gov/pubmed/36159844
http://dx.doi.org/10.3389/fimmu.2022.982821

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