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Maturation of circulating Ly6C(hi)CCR2(+) monocytes by mannan-MOG induces antigen-specific tolerance and reverses autoimmune encephalomyelitis

Autoimmune diseases affecting the CNS not only overcome immune privilege mechanisms that protect neural tissues but also peripheral immune tolerance mechanisms towards self. Together with antigen-specific T cells, myeloid cells are main effector cells in CNS autoimmune diseases such as multiple scle...

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Detalles Bibliográficos
Autores principales: Dagkonaki, Anastasia, Papalambrou, Athina, Avloniti, Maria, Gkika, Areti, Evangelidou, Maria, Androutsou, Maria-Eleni, Tselios, Theodore, Probert, Lesley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501702/
https://www.ncbi.nlm.nih.gov/pubmed/36159850
http://dx.doi.org/10.3389/fimmu.2022.972003