Cargando…
Maturation of circulating Ly6C(hi)CCR2(+) monocytes by mannan-MOG induces antigen-specific tolerance and reverses autoimmune encephalomyelitis
Autoimmune diseases affecting the CNS not only overcome immune privilege mechanisms that protect neural tissues but also peripheral immune tolerance mechanisms towards self. Together with antigen-specific T cells, myeloid cells are main effector cells in CNS autoimmune diseases such as multiple scle...
Autores principales: | Dagkonaki, Anastasia, Papalambrou, Athina, Avloniti, Maria, Gkika, Areti, Evangelidou, Maria, Androutsou, Maria-Eleni, Tselios, Theodore, Probert, Lesley |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501702/ https://www.ncbi.nlm.nih.gov/pubmed/36159850 http://dx.doi.org/10.3389/fimmu.2022.972003 |
Ejemplares similares
-
Mannan-MOG35-55 Reverses Experimental Autoimmune Encephalomyelitis, Inducing a Peripheral Type 2 Myeloid Response, Reducing CNS Inflammation, and Preserving Axons in Spinal Cord Lesions
por: Dagkonaki, Anastasia, et al.
Publicado: (2020) -
Characterization of Asparagine Deamidation in Immunodominant Myelin Oligodendrocyte Glycoprotein Peptide Potential Immunotherapy for the Treatment of Multiple Sclerosis
por: Androutsou, Maria-Eleni, et al.
Publicado: (2020) -
CCR2 Deficiency Impairs Ly6C(lo) and Ly6C(hi) Monocyte Responses in Orientia tsutsugamushi Infection
por: Petermann, Michael, et al.
Publicado: (2021) -
Helminth-induced Ly6C(hi) monocyte-derived alternatively activated macrophages suppress experimental autoimmune encephalomyelitis
por: Terrazas, Cesar, et al.
Publicado: (2017) -
Histopathology and clinical course of MOG-antibody-associated encephalomyelitis
por: Spadaro, Melania, et al.
Publicado: (2015)