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Broad genomic workup including optical genome mapping uncovers a DDX3X: MLLT10 gene fusion in acute myeloid leukemia

In acute myeloid leukemia (AML), treatment decisions are currently made according to the risk classification of the European LeukemiaNet (ELN), which is based on genetic alterations. Recently, optical genome mapping (OGM) as a novel method proved to yield a genome-wide and detailed cytogenetic chara...

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Detalles Bibliográficos
Autores principales: Nilius-Eliliwi, Verena, Tembrink, Marco, Gerding, Wanda Maria, Lubieniecki, Krzystof P., Lubieniecka, Joanna M., Kankel, Stefanie, Liehr, Thomas, Mika, Thomas, Dimopoulos, Fotios, Döhner, Konstanze, Schroers, Roland, Nguyen, Hoa Huu Phuc, Vangala, Deepak Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501710/
https://www.ncbi.nlm.nih.gov/pubmed/36158701
http://dx.doi.org/10.3389/fonc.2022.959243