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A New Class of Tunable Acid-Sensitive Linkers for Native Drug Release Based on the Trityl Protecting Group

[Image: see text] Core-cross-linked polymeric micelles (CCPMs) are a promising nanoparticle platform due to favorable properties such as their long circulation and tumor disposition exploiting the enhanced permeability and retention (EPR) effect. Sustained release of covalently linked drugs from the...

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Detalles Bibliográficos
Autores principales: Timmers, Matt, Weterings, Jimmy, van Geijn, Michiel, Bell, Roel, Lenting, Peter E., Rijcken, Cristianne J.F., Vermonden, Tina, Hennink, Wim E., Liskamp, Rob M.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501768/
https://www.ncbi.nlm.nih.gov/pubmed/35979909
http://dx.doi.org/10.1021/acs.bioconjchem.2c00310