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Hybridization-Sensitive Fluorescent Probes for DNA and RNA by a Modular “Click” Approach

[Image: see text] Fluorescent DNA probes were prepared in a modular approach using the “click” post-synthetic modification strategy. The new glycol-based module and DNA building block place just two carbons between the phosphodiester bridges and anchor the dye by an additional alkyne group. This cre...

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Detalles Bibliográficos
Autores principales: Gebhard, Julian, Hirsch, Lara, Schwechheimer, Christian, Wagenknecht, Hans-Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501807/
https://www.ncbi.nlm.nih.gov/pubmed/35995426
http://dx.doi.org/10.1021/acs.bioconjchem.2c00241