Cargando…

Cranberry Ingestion Modulated Drug Transporters and Metabolizing Enzymes: Gefitinib Used as a Probe Substrate in Rats

Cranberry, a polyphenol-rich functional food, is commonly used for the prophylaxis of urinary tract infections. Gefitinib, an anticancer agent clinically prescribed to treat non-small-cell lung cancer, is a substrate of P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP), and metaboliz...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Chung-Ping, Tsai, Pei-Ling, Li, Pei-Ying, Hsu, Pei-Wen, Lin, Shiuan-Pey, Lee Chao, Pei-Dawn, Hou, Yu-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501900/
https://www.ncbi.nlm.nih.gov/pubmed/36144507
http://dx.doi.org/10.3390/molecules27185772