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Cranberry Ingestion Modulated Drug Transporters and Metabolizing Enzymes: Gefitinib Used as a Probe Substrate in Rats

Cranberry, a polyphenol-rich functional food, is commonly used for the prophylaxis of urinary tract infections. Gefitinib, an anticancer agent clinically prescribed to treat non-small-cell lung cancer, is a substrate of P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP), and metaboliz...

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Detalles Bibliográficos
Autores principales:	Yu, Chung-Ping, Tsai, Pei-Ling, Li, Pei-Ying, Hsu, Pei-Wen, Lin, Shiuan-Pey, Lee Chao, Pei-Dawn, Hou, Yu-Chi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501900/ https://www.ncbi.nlm.nih.gov/pubmed/36144507 http://dx.doi.org/10.3390/molecules27185772

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