Moving Protein PEGylation from an Art to a Data Science

[Image: see text] PEGylation is a well-established and clinically proven half-life extension strategy for protein delivery. Protein modification with amine-reactive poly(ethylene glycol) (PEG) generates heterogeneous and complex bioconjugate mixtures, often composed of several PEG positional isomers...

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Detalles Bibliográficos
Autores principales: Mao, Leran, Russell, Alan J., Carmali, Sheiliza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501918/
https://www.ncbi.nlm.nih.gov/pubmed/35994522
http://dx.doi.org/10.1021/acs.bioconjchem.2c00262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501918/
https://www.ncbi.nlm.nih.gov/pubmed/35994522
http://dx.doi.org/10.1021/acs.bioconjchem.2c00262

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